Professor Jim Mann
Jim Mann has been Professor in Human Nutrition and Medicine at the University of Otago and Consultant Physician (Endocrinology) in Dunedin Hospital for 22 years. In the preceding years he lectured at the University of Oxford and worked as a Consultant Physician in the Radcliffe Infirmary.
He is also the Director of the Edgar National Centre for Diabetes and Obesity Research (ENCDOR) and the WHO Collaborating Centre for Human Nutrition. His research has principally been in the fields of lipids and carbohydrates as they relate to coronary heart disease and diabetes and in the field of obesity. However he has also been particularly interested in the role of obesity as a cause of cancer and was a member of the Advisory Group and Panel of the World Cancer Research Fund (WCRF) which produced the 2007 Report on “Food, Nutrition, Physical Activity and the Prevention of Cancer”, followed by the 2009 Policy Report, “Policy and Action for Cancer Prevention”.
He has been author and coauthor of over 300 papers published in peer reviewed journals and written and edited several textbooks and popular books, including the “Essentials of Human Nutrition” (co-edited with Professor Stewart Truswell) which was published by Oxford University Press. The Third Edition of this textbook was published in April 2007 and the fourth edition will follow in 2011.
He has been involved with a number of international and national organisations concerned with diabetes and nutrition and health, several of which he has chaired or continues to chair. These include the Diabetes and Nutrition Study Group of the European Association for the study of Diabetes,) the Evidence Based Nutrition panel of the International Union of Nutritional Sciences (IUNS) and several WHO/FAO Expert Advisory Groups and Scientific Update Groups. He has recently been appointed to the WHO Nutrition Guidance Group (NUGAG).
In New Zealand, Professor Mann currently chairs the Ministry of Health Expert Advisory Group on Diabetes and Cardiovascular Disease and the Panels developing implementation plans for updated diabetes and obesity guidelines.
As Principal Investigator he was awarded the international Bristol-Myers Squibb/Mead Johnson Unrestricted Grant for Human Nutrition, was the third recipient of the University of Otago Distinguished Research Medal in 2002 and in 2004 he received the Sir Charles Hercus Medal of the Royal Society of New Zealand. He was appointed a Companion of the New Zealand Order of Merit for services to Medicine in 2003. He was also awarded the Distinguished Researcher Award from the Dunedin School of Medicine for 2005.
Community Involvement
Professor Mann serves as Medical Advisor to Diabetes New Zealand with particular reference to their publication “Diabetes”, Patron of Diabetes Otago and Trustee of several diabetes related charitable trusts. He is frequently invited to talk to community based organisations including Rotary Clubs, University of the Third Age, and local Diabetes Societies. He has been Honorary Consul for Finland since 2005.
Major research publications
McAuley KA, Berkeley JE, Docherty PD, Lotz TF, Te Morenga LA, Shaw GM, Williams SM, Chase JG, Mann JI: The dynamic insulin sensitivity and secretion test-a novel measure of insulin sensitivity. Metabolism 2011 Jun 23. [Epub ahead of print]. DOI 10.1016/j.metabol.2011.05.009
Coppell KJ, Lee J(E), Williams SM, Mann JI. Progression of glycaemia and cardiovascular risk factors in patients of different age groups with new type 2 diabetes over 5 years of follow-up in a diabetes quality improvement initiative. Diabetes Research and Clinical Practice 2011; [Epub ahead of print]. doi:10.1016/j.diabres.2011.04.021
Te Morenga LA, Levers MT, Williams SM, Brown RC, Mann J. Comparison of high protein and high fiber weight-loss diets in women with risk factors for the metabolic syndrome: a randomized trial. Nutrition Journal 2011, 10:40
Taylor RW, Farmer VL, Cameron SL, Meredith-Jones K, Williams SM, Mann JI. School playgrounds and physical activity policies as predictors of school and home time activity. International Journal of Behavioral Nutrition and Physical Activity 2011, 8:38
Docherty, PD, Chase, JG, Lotz, TF, Hann, CE, Shaw, GM, Berkeley, JE, TeMorenaga, L, Mann, JI and McAuley, KA (2011). "Independent Cohort Cross-validation of the Real-time DISTq Estimation of Insulin Sensitivity," Computer Methods and Programs in Biomedicine, Vol 102(2), pp. 94-104, ISSN: 0169-2607 (invited).
Coppell KJ, Kataoka M, Williams SM, Chisholm AW, Vorgers SM, Mann JI. Nutritional intervention in patients with type 2 diabetes who are hyperglycaemic despite optimised drug treatment—Lifestyle Over and Above Drugs in Diabetes (LOADD) study: randomised controlled trial. BMJ 2010;341:c3337 doi: 101136/bmj.c3337
Taylor RW, Brooking L, Williams SM, Manning PJ, Sutherland WH, Coppell KJ, Tipene-Leach D, Dale KS, McAuley KA, Mann JI. Body mass index and waist circumference cutoffs to define obesity in indigenous New Zealanders. American Journal of Clinical Nutrition 2010;92(2):390-397.
McAuley KA, Taylor RW, Farmer VL, Hansen P, Williams SM, Booker CS, Mann JI. Economic evaluation of a community-based obesity prevention program in children: the APPLE project. Obesity (Silver Spring) 2010 Jan;18(1):131-6. Epub 2009 May 14
Key TJ, Appleby PN, Spencer EA, Travis RC, Allen NE, Thorogood M, Mann JI. Cancer Incidence in British vegetarians. Br J Cancer. 2009, 101 (1): 192-7
Coppell KJ, Tipene-Leach DC, Pahau HLR, Williams SM, Abel S, Iles M, Harré Hindmarsh J, Mann JI. Two-year results from a community-wide diabetes prevention intervention in a high risk indigenous community: The Ngati and Healthy project. Diabetes Res Clin Pract. 2009; 85:(2):220-7.
Dale K, McAuley KA, Taylor RW, Williams SM, Farmer VL, Hansen P, Vorgers SM, Chisholm AW, Mann JI. Determining optimal approaches for successful weight maintenance: A 2 x 2 factorial randomised controlled trial. Canadian Medical Association Journal 2009 180(10): E39-E46.
Taylor RW, McAuley KA, Barbezat W, Farmer VL, Williams SM, Mann JI. Two-year follow-up of an obesity prevention initiative in children: the?APPLE project. Am J Clin Nutr. 2008; 88 (5):1371–7.
Editorials for international journals
Mann J, Nye ER. Fad diets in Sweden, of all places. The Lancet. 2009, 374: 767 - 765
Mann J, Vegetarian diets. BMJ 2009;339:b2507
Cummings JH, Mann JI, Nishida C, Vorster HH. Dietary fibre: an agreed definition. The Lancet. 2009; 373: 365 - 366
Mann J, Aune D. Can specific fruits and vegetables prevent diabetes?
BMJ. 2010 18;341:c4395. doi: 10.1136/bmj.c4395.
Major reports
Ministry of Health and Clinical Trials Research Unit. 2009. Clinical Guidelines for Weight Management in New Zealand Adults. Wellington: Ministry of Health.ISBN 978-0-478-33987-1. HP 5014
Ministry of Health and Clinical Trials Research. 2009.Clinical Guidelines for Weight Management in New Zealand Children and Young People. Wellington: Ministry of Health ISBN number: 978-0-478-33994-9 (online) HP number: 5026
Ministry of Health. Diabetes and Cardiovascular Disease Quality Improvement Plan (QIP). 2008. Wellington: Ministry of Health. ISBN 978-0-478-31260-7. ISBN 978-0-478-31261-4
World Cancer Research Fund/American Institute for Cancer Research. Food, nutrition, physical activity and the prevention of cancer: a global perspective. AICR, 2007. www.dietandcancerreport.org/.
Booker CS, Mann JI. Trans fatty acids and cardiovascular health: Translation of the evidence base. Nutr Metab Cardiovasc Dis. 2008; 18(6):448-56.
Book chapters (2008 – 2011)
Te Morenga L, Mann J. Nutrition: its relevance in Development and Treatment of the Metabolic Syndrome (2011). In: The Metabolic Syndrome Second Edition. Byrne C, Wild S (eds), Blackwell Publishing Ltd. Chichester, UK. Chapter 17, pp 297 – 326
Mann J. Chapter 19: Cardiovascular Disease. In: Geissler C, Powers H, editors. Human Nutrition. Elsevier Limited: 2011. p. 383-399 Publications: 2011
Diseases of overnourished societies and the need for dietary change. In OxfordTextbook of Medicine, 5th edition. DA Warrell, TM Cox, JD Firth (eds). (CoauthorAS Truswell) Oxford University Press, Oxford (2010) Chapter 11.4 (Volume 1).
J Mann, M Toeller. Epidemiology of Nutrition and Diabetes Mellitus: Etiology and Environmental Factors: (2008) In The Epidemiology of Diabetes Mellitus Second Edition, Ekoe et al (eds) John Wiley & Sons, Ltd. Chapter 7, pp 87 - 94
M Toeller, J Mann. Nutrition in the etiology and management of type 2 diabetes: (2008) In Textbook of Type 2 Diabetes Principles and Practice, Second Edition. BJ Goldstein and D Müller-Wieland (eds) Informa Healthcare (New York). Chapter 5, p. 59 - 71
Important Past Publications
Mann J, Vegetarian diets. BMJ 2009;339:b2507
Key TJ, Appleby PN, Spencer EA, Travis RC, Allen NE, Thorogood M, Mann JI. Cancer Incidence in British vegetarians. Br J Cancer. 2009, 101 (1): 192-7
Dale K, McAuley KA, Taylor RW, Williams SM, Farmer VL, Hansen P, Vorgers SM, Chisholm AW, Mann JI. Determining optimal approaches for successful weight maintenance: A 2 x 2 factorial randomised controlled trial. Canadian Medical Association Journal 2009 180(10): E39-E46.
Mann JI, Cummings JH. Possible implications for health of the different definitions of dietary fibre. Nutr Metab Cardiovasc Dis. 2009; 19: 226-229.
Taylor RW, McAuley KA, Barbezat W, Farmer VL, Williams SM, Mann JI. Two-year follow-up of an obesity prevention initiative in children: the?APPLE project. Am J Clin Nutr. 2008; 88 (5):1371–7.
Mann J. Dietary carbohydrate: relationship to cardiovascular disease and disorders of carbohydrate metabolism. Eur J Clin Nutr. 2007; 61(Suppl 1): S100-S111.
Mann JI, Cummings JH, Englyst HN, Key T, Liu S, Riccardi G, Summerbell C, Uauy R, van Dam RM, Venn B, Vorster HH, Wiseman M. FAO/WHO Scientific Update on carbohydrates in human nutrition: conclusions. Eur J Clin Nutr. 2007; 61(Suppl 1): S132-S137
Taylor RW, McAuley KA, Barbezat W, Strong A, Williams SM, Mann JI. APPLE Project: 2-y findings of a community-based obesity prevention program in primary school age children. Am J Clin Nutr. 2007; 86(3): 735-42.
Taylor RW, McAuley KA, Williams SM, Barbezat W, Nielsen G, Mann JI (2006). Reducing weight gain in children through enhancing physical activity and nutrition: The APPLE project. International Journal of Pediatric Obesity 1(3): 146-152
McAuley K, Mann J. (2006) Nutritional determinants of insulin resistance. Journal of Lipid Research 47: 1668 – 1676
McAuley KA, Smith KJ, Taylor RW, McLay RT, Williams SM, Mann JI. (2006) Long-term effects of popular dietary approaches on weight loss and features of Insulin resistance. International journal of Obesity. 30: 342 – 9
Mann JI, De Leeuw I, Hermansen K, Karamanos B, Karlstrom B,Katsilambros, NRiccardi G, Rivellese AA, Rizkalla S, Slama, G, Toeller M, Uusitupa M, Vessby B. (2004) Evidence-based nutritional approaches to the treatment and prevention of diabetes mellitus. Nutrition, Metabolism and Cardiovascular Diseases 14: 373-394
Venn BJ, Mann JI. (2004) Cereal grains, legumes and diabetes. European Journal of Clinical Nutrition 58: 1443-1461.
Mann J. Free sugars and human health: sufficient evidence for action? (2004) Lancet 363: 1068-1070.
Venn BJ, Mann JI, Williams SM, Riddell LJ, Chisholm A, Harper MJ, Aitken W. (2002) Dietary counseling to increase natural folate intake: a randomized placebo-controlled trial in free-living subjects to assess effects on serum folate and plasma total homocysteine. American Journal of Clinical Nutrition 76: 758-65.
Mann J. (2002) Diet and risk of coronary heart disease and type 2 diabetes. Lancet 360: 783-789.
Elsmlie J, Mann JI, JT Silverstone, Williams SM, Romans SE (2001). Determinants of overweight and obesity in patients with bipolar disorder. Journal of Clinical Psychiatry 62: 486-491.
McAuley KA, Williams SM, Mann JI, Walker RJ, Lewis-Barned NJ, Temple LA, Duncan AW (2001) Diagnosing insulin resistance in the general population. Diabetes Care 24: 460-464.
Mann JI (2000). Stemming the tide of diabetes. Lancet 356: 1454-1455.
Riddell LJ, Chisholm A, Williams S, Mann JI. Dietary strategies for lowering homocysteine concentrations (2000) American Journal of Clinical Nutrition 71: 1448-1454.
Thomas MC, Mann J. (1998) Increased thrombotic vascular events after change of statin. Lancet 352: 1830-1831.
Mann JI, Appleby PN, Key TJ, Thorogood M (1997) Dietary determinants of ischaemic heart disease in health conscious individuals. Heart 78: 450-455.
Zino S, Skeaff M, Williams S, Mann J. (1997) Randomised controlled trial of effect of fruit and vegetable consumption on plasma concentrations of lipids and antioxidants. British Medical Journal 314: 1787-1791.
Chisholm A, Mann JI, Sutherland W, Duncan A, Skeaff CM, Frampton C. (1996) Effect on lipoprotein profile of replacing butter with margarine in a low fat diet: randomised crossover study with hypercholesterolaemic subjects. British Medical Journal 312: 931-934.
Cox C, Mann J, Sutherland W, Ball M. (1995) Individual variation in plasma cholesterol response to dietary saturated fat. British Medical Journal 311: 1260-1264.
Bourn DM, Mann JI, McSkimming BJ, Waldron MA, Wishart JD (1994) Impaired glucose tolerance and NIDDM: Does a lifestyle intervention program have an effect? Diabetes Care 17(11): 1311-1319.
Peterson DB, Fisher K, Carter RD and Mann, J (1994) Fatty acid
composition of erthrocytes and plasma triglyceride and cardiovascular risk in Asian diabetic patients. Lancet 343: 1528-1530.
Mann JI, Crooke M, Fear H, Hay DR, Jackson RT, Neutze JM, White HD (1993) Guidelines for detection and management of dyslipidaemia. New Zealand Medical Journal 106, 133-141.
Mann JI, Lewis B, Shepherd J, Winder AF, Fenster S, Rose L, Morgan B (1988) Blood lipid concentrations and other cardiovascular risk factors: distribution, prevalence and detection in Britain. British Medical Journal 296, 1702-1706.
Pixley F, Mann JI (1988) Dietary factors in the aetiology of gall stones: a case control study. Gut 29, 1511-1515.
Thorogood M, Carter R, Benfield L, McPherson K, Mann JI (1987) Plasma lipids and lipoprotein cholesterol concentrations in people with different diets in Britain. British Medical Journal 295, 351-353.
Baron JA, Schori A, Crow B, Carter R, Mann JI (1986) A randomised controlled trial of low carbohydrate and low fat/high fibre diets for weight loss. American Journal of Public Health 75, 1293-1296.
Peterson DB, Lambert J, Gerring S, Darling P, Carter RD, Jelfs R, Mann JI (1986) Sucrose in the diet of diabetic patients - just another carbohydrate? Diabetologia 29, 216-220.
Lewis B, Mann JI, Mancini M (1986) Reducing the risks of coronary heart disease in individuals and in the population. Lancet I, 956-959.
Geekie MA, Porteous J, Hockaday TDR, Mann JI (1986) Acceptability of high-fibre diets in diabetic patients. Diabetic Medicine 3, 65-68.
Pixley F, Wilson D, McPherson K, Mann JI (1985) Effect of vegetarianism on development of gallstones in women. British Medical Journal 291, 11-12.
Mann JI (1984) Lines to legumes: changing concepts of diabetic diets. Diabetic Medicine 1, 191-198.
Simpson HCR, Mann JI, Meade TW, Chakrabarti R, Stirling Y, Woolf L (1983) Hypertriglyceridaemia and hypercoagulability. Lancet I, 786-790.
Dornan TL, Mann JI, Turner RC (1982) Factors protective against retinopathy in insulin-dependent diabetics free of retinopathy for 30 years. British Medical Journal 285, 1073-1077.
Simpson HCR, Barker K, Carter RD, Cassells E, Mann JI (1982) Low dietary intake of linoleic acid predisposes to myocardial infarction. British Medical Journal 285, 683-684.
Simpson HCR, Simpson RW, Lousley S, Carter RD, Geekie M, Hockaday TDR, Mann JI (1981) A high carbohydrate leguminous fibre diet improves all aspects of diabetic control. Lancet I, 1-5.
Gear JSS, Ware AC, Fursdon P, Mann JI, Nolan DJ, Brodribb A, Vessey MP (1979) Symptomless diverticular disease and intake of dietary fibre. Lancet I, 511-514.
Mann JI (1979) Fats and atheroma: a retrial. British Medical Journal 1, 732-734.
Simpson RW, Mann JI, Hockaday JM, Turner RC, Jelfs R (1979) Lipid abnormalities in untreated maturity-onset diabetics and the effect of treatment. Diabetologia 16, 101-106.
Bottazzo GF, Mann JI, Thorogood M, Baum JD, Doniach D (1978) Autoimmunity in juvenile diabetics and their families. British Medical Journal 2, 165-168.
Hughson WG, Mann JI, Tibbs DJ, Woods HF, Walton I (1978) Intermittent claudication: factors determining outcome. British Medical Journal 1, 1377-1379.
Mann JI, Doll R, Thorogood M, Vessey MP, Waters WE (1976) Risk factors for myocardial infarction in young women. British Journal of Preventive and Social Medicine 30, 94-100.
Mann JI, Inman WHW (1975) Oral contraceptives and death from myocardial infarction. British Medical Journal 2, 245-248.
Mann JI, Truswell AS (1972) Effects of isocaloric exchange of dietary sucrose and starch on fasting serum lipids, postprandial insulin secretion and alimentary lipaemia in human subjects. British Journal of Nutrition 27, 395-405.
Mann JI, Truswell AS, Hendricks D, Manning EB (1970) Effects on serum lipids in normal men of reducing dietary sucrose or starch for five months. Lancet I, 870-872.